- / CL Answers
- / I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug?
Our Members Asked:
I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug?
Reviewed and edited by Tod Cooperman, M.D.
Answer:Omeprazole (Prilosec), Nexium, and other proton pump inhibitor drugs can be affected by taking supplements, and can affect your ability to absorb certain vitamins and minerals. St. John's wort, for example, should not be taken with these drugs.
Be sure to also read about magnesium depletion which can occur with these drugs in the Magnesium Supplements Review. And, if you take a calcium supplement, read in the Calcium Supplements Review how certain forms of calcium may be preferable if you are taking these drugs.
Also see our CL Answer about supplements for indigestion and heartburn.
Join today to unlock all member benefits including full access to all CL Answers and over 1,300 reviews.Join Now
Already a member? Sign In Here.
Join now at www.consumerlab.com/join/
Related CL Answers (17)
Which supplements can help with indigestion and/or heartburn?
Information on supplements for heartburn that can help relieve gastrointestinal symptoms - heartburn, indigestion and acid reflux.
Is there a danger of getting too much calcium from Tums? I take them frequently for heartburn.
How many Tums should you be taking? Learn more about exceeding the recommended daily intake of calcium with Tums.
Which supplements make acid reflux worse? I take many and think some are causing heartburn. Are there any supplements that help treat acid reflux?
Find out which supplements can cause or worsen acid reflux, nausea and GERD, including vitamin B6, arginine, and CoQ10.
I take St. John's wort for depression. Your report notes that it can interact with other medications. Would taking it several hours apart from other meds avoid this interaction?
St. John's wort (Hypericum perforatum) can interact with other medications, but can this be avoided by spacing out the dosages?
I read that turmeric may be a GI irritant. I have GI problems and wonder if I should avoid turmeric and curcumin?
Find out if turmeric/curcumin supplements can cause gastrointestinal irritability.
Can melatonin help with stomach pain?
Find out if melatonin supplements can help with stomach pain, ulcers, reflux and dyspepsia, or if it can cause stomach upset.
Is it true that low-carb or Mediterranean diets help for gastroesophageal reflux disease (GERD)?
Find out if a low-carb diet, such as the Mediterranean diet, or lifestyle changes help with gastroesophageal reflux disease (GERD).
Do vitamin patches, such as for B12 or multivitamins, really work? How about those from PatchMD?
Do vitamin B12 Patches like PatchMD really work? Can you absorb vitamin B12 through patches?
What B-vitamin complex do you recommend for older people?
Vitamin B complex supplement recommendations, benefits and top rated brands for older people and all ages.
I've heard that grapefruit juice can interact with medications because it inhibits an enzyme that breaks down drugs in the body. Do any supplements interact the same way with drugs?
CYP3A4 inhibitors, such as grapefruit, can interact with certain medications by inhibiting the liver enzyme that metabolizes many drugs. ConsumerLab.com's answer explains.
How much magnesium do I need and how much magnesium from supplements is too much?
Find out how much magnesium you should be getting on a daily basis, signs of magnesium deficiency, and how much magnesium is too much, particularly from magnesium supplements and laxatives containing magnesium. Find out the side effects and potential adverse effects of too much magnesium.
Are there any supplements I should avoid when taking acetaminophen (Tylenol)?
Find out if there are any supplements that should be avoided when taking acetaminophen (Tylenol).
Do supplements help treat peptic ulcer disease? Should any be avoided?
Vitamins and supplements that may help with peptic ulcer disease, including probiotics, cranberry, melatonin, lactoferrin, berberine, and licorice.
What are the most common, potentially dangerous interactions between supplements and drugs?
Info on the most common, potentially dangerous, interactions between drugs & supplements, including Lisinopril interactions and others.
Do any supplements help for ulcerative colitis?
Find out what supplements & vitamins can help with ulcerative colitis, such as VSL#3, curcumin, aloe or boswellia.
Does taking a laxative interfere with the absorption of vitamins or minerals?
Information on laxative interactions with other medications and supplements such as Maalox, antibiotics, and statins and diabetes medications.